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mouse pancreatic islet β cell line nit 1  (ATCC)


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    ATCC mouse pancreatic islet β cell line nit 1
    Mouse Pancreatic Islet β Cell Line Nit 1, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 240 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse pancreatic islet β cell line nit 1/product/ATCC
    Average 95 stars, based on 240 article reviews
    mouse pancreatic islet β cell line nit 1 - by Bioz Stars, 2026-02
    95/100 stars

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    Effect of up- and downregulated VEGFB on serum insulin and β cell function index. (A) Serum insulin contents of WT, STZ-WT and STZ-KO mice (n=10). (B-D) HOMA-β, ΔI30/ΔG30, and MBCI of WT, STZ-WT and STZ-KO mice (n=10). *P<0.05 vs. WT; # P<0.05 vs. STZ-WT. (E) Serum insulin contents of WT, AAV-control and AAV–VEGFB 186 mice (n=10). (F-H) HOMA-β, ΔI30/ΔG30, and MBCI of WT, AAV-control and AAV–VEGFB 186 mice (n=10). *P<0.05 vs. WT; # P<0.05 vs. AAV-control. VEGFB, vascular endothelial growth factor B; STZ, streptozocin; WT, wild type; KO, knockout; AAV, adeno-associated virus.

    Journal: Molecular Medicine Reports

    Article Title: Vascular endothelial growth factor B regulates insulin secretion in β cells of type 2 diabetes mellitus mice via PLCγ and the IP3R‑evoked Ca2 + /CaMK2 signaling pathway

    doi: 10.3892/mmr.2023.13084

    Figure Lengend Snippet: Effect of up- and downregulated VEGFB on serum insulin and β cell function index. (A) Serum insulin contents of WT, STZ-WT and STZ-KO mice (n=10). (B-D) HOMA-β, ΔI30/ΔG30, and MBCI of WT, STZ-WT and STZ-KO mice (n=10). *P<0.05 vs. WT; # P<0.05 vs. STZ-WT. (E) Serum insulin contents of WT, AAV-control and AAV–VEGFB 186 mice (n=10). (F-H) HOMA-β, ΔI30/ΔG30, and MBCI of WT, AAV-control and AAV–VEGFB 186 mice (n=10). *P<0.05 vs. WT; # P<0.05 vs. AAV-control. VEGFB, vascular endothelial growth factor B; STZ, streptozocin; WT, wild type; KO, knockout; AAV, adeno-associated virus.

    Article Snippet: Mouse islet β cell line Min6 was purchased from the Procell Life Science&Technology Company and was cultured in RPMI-1640 (Gibco; Thermo Fisher Scientific, Inc.) medium containing 10% fetal bovine serum, and 1% Penicillin/streptomycin (P/S).

    Techniques: Cell Function Assay, Control, Knock-Out, Virus